Applications of antimicrobial peptides derived from the defensin of the rhinoceros beetle Allomyrina dichotoma

JUN ISHIBASHI - Juntendo Medical Journal, 2016 - jstage.jst.go.jp
… To test the antigenicity of the defensin-derived AMPs, they … The defensin-derived AMPs disrupt
the membrane in a mouse … We examined the cytotoxicity of the peptide-immobilized fibers …

The medical potential of antimicrobial peptides from insects

M Tonk, A Vilcinskas - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
… of novel insect-derived AMPs, including potential cytotoxic, … sensitive to defensin from the
beetle Allomyrina dichotoma [54… against the mouse myeloma cell line P3-X63Ag8.653. Flow …

[HTML][HTML] Korean Edible Insects: A Promising Sustainable Resource of Proteins and Peptides for Formulating Future Functional Foods

NE Wedamulla, Q Zhang, SH Kim, YJ Choi… - Food Supplements and …, 2024 - e-fsbh.org
… investigated the inhibitory activity of peptides derived from B. mori on … peptides with minimal
cytotoxicity was demonstrated using … defensin to find the peptide with increased antimicrobial

Design of a helical-stabilized, cyclic, and nontoxic analogue of the peptide Cm-p5 with improved antifungal activity

FEM Vicente, M González-Garcia, E Diaz Pico… - ACS …, 2019 - ACS Publications
… to fluconazole, its low cytotoxicity, together with a stabilized α-… Cm-p5 (SRSELIVHQRLF-NH
2 ) is a peptide derived from a … that are present in insulin and defensins. However, this is the …

[HTML][HTML] Nutritional composition, health benefits, and application value of edible insects: a review

Y Zhou, D Wang, S Zhou, H Duan, J Guo, W Yan - Foods, 2022 - mdpi.com
… Some active peptides from insects also show cytotoxicity … [166], antimicrobial peptides based
on insect defensin [167], … For example, hydrolyzed peptides obtained by heat treatment from …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
… Furthermore, a brevinin-1 peptide derived from the skin … in the mice and protected the infected
mice from bacterial … Interestingly, in addition to being non-cytotoxic, the peptide activity was …

[HTML][HTML] Clinical potential of engineered cationic antimicrobial peptides against drug resistant biofilms

JA Melvin, RC Montelaro… - Expert review of anti …, 2016 - Taylor & Francis
… eCAPs are synthetic peptides designed based on natural AMP sequences and structures …
Antigenicity of eCAPs is also a possibility, though even during covalent linkage to antigenic

[HTML][HTML] The draft genome sequence of the Japanese rhinoceros beetle Trypoxylus dichotomus septentrionalis towards an understanding of horn formation

S Morita, TF Shibata, T Nishiyama, Y Kobayashi… - Scientific Reports, 2023 - nature.com
The Japanese rhinoceros beetle Trypoxylus dichotomus is a giant beetle with distinctive
exaggerated horns present on the head and prothoracic regions of the male. T. dichotomus has …

Roles and Biomedical Applications of Haemolymph Lectin

R Kamei, OS Devi, SJ Singh… - Current Pharmaceutical …, 2020 - ingentaconnect.com
… This cytotoxic effect of MytiLec is specifically blocked by the co-… (SC-28 strain), obtained from
the blood of infected mice. While R. … big defensin [60]. Studies on serum lectin from a grub of …

Tenebrio molitor as a source of interesting natural compounds, their recovery processes, biological effects, and safety aspects

S Errico, A Spagnoletta, A Verardi… - … Reviews in Food …, 2022 - Wiley Online Library
… They investigated the possible cytotoxicity of the powder used as food by assessing the …
Aqueous lipid extraction produced the lowest total extracted lipid value for all insect types (…